Intensive care unit ventilator and patient monitor at bedside
CuffWay logo

Innovations for safer airways.

Automated, adaptive cuff pressure control, built to help prevent airway injury.

Built by a founding team with 6 ventures and 4 exits across medtech and SaaS

The Problem

An estimated 9 million patients undergo tracheal intubation in U.S. hospitals each year. 72% of patients have unsafe cuff pressures and 57% experience tracheal complications. Intubation lasting 48 hours or more increases the risk of tissue injury and aspiration.

Why complications occur

  1. Cuffs are staticThe trachea expands and contracts. A fixed cuff must seal it at its widest, leaving sustained pressure on the tissue as the airway narrows.
  2. Monitoring is manualClinicians check and adjust pressure every 2 to 4 hours, spending up to 2 hours a day on repeated bedside visits.

The Solution

CuffWay is developing continuous cuff pressure monitoring and control. It adjusts pressure as the airway moves to maintain a seal without unnecessary force on the tracheal wall.

  1. Pressure that adaptsThe system responds to breathing, coughing and movement, adjusting cuff pressure in real time to keep a seal as the airway changes.
  2. Fits the bedside workflowA reusable controller connects through a disposable tube set. Setup takes less than 30 seconds, with continuous monitoring instead of manual checks.
Intubation anatomy diagram showing the endotracheal tube sealed in the trachea
Complication Cost

+1.1 ICU days + $2,000 in hospital costs. [1]

Readmission Impact

+4.7 ICU days + $11,025 per readmission. [1]

CuffWay bedside controller connected to a test lung and bag-valve maskClose-up of the CuffWay controller displaying live cuff pressure
CuffWay controller and lung test setup.

[1] Bhatti NI. Cost analysis of intubation-related tracheal injury using a national database. Otolaryngol Head Neck Surg. 2010.

Traction & Milestones

Click through the milestones

Preclinical studies in pig tracheas

43%tracheal pressure reduction with CuffWay vs standard care
100%tidal volume maintained
$600Kestimated annual hospital savings
730%estimated first-year ROI